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Alternate therapeutic pathways for PARP inhibitors and potential mechanisms  of resistance | Experimental & Molecular Medicine
Alternate therapeutic pathways for PARP inhibitors and potential mechanisms of resistance | Experimental & Molecular Medicine

PARPtrap™ Assay Kit for PARP1
PARPtrap™ Assay Kit for PARP1

PARP1 inhibitors trigger innate immunity via PARP1 trapping-induced DNA  damage response | eLife
PARP1 inhibitors trigger innate immunity via PARP1 trapping-induced DNA damage response | eLife

Unsprung traps keep PARP inhibitors effective | Nature Cell Biology
Unsprung traps keep PARP inhibitors effective | Nature Cell Biology

Setting a Trap for PARP1 and PARP2
Setting a Trap for PARP1 and PARP2

Cancers | Free Full-Text | PARP Inhibitors Resistance: Mechanisms and  Perspectives
Cancers | Free Full-Text | PARP Inhibitors Resistance: Mechanisms and Perspectives

Frontiers | Perspectives on PARP Inhibitor Combinations for Ovarian Cancer
Frontiers | Perspectives on PARP Inhibitor Combinations for Ovarian Cancer

JCM | Free Full-Text | PARP Inhibitors as a Therapeutic Agent for  Homologous Recombination Deficiency in Breast Cancers
JCM | Free Full-Text | PARP Inhibitors as a Therapeutic Agent for Homologous Recombination Deficiency in Breast Cancers

Piet Ost on X: "How does PARPinhibitors work? By Kim Chi. Not all molecules  do PARP trapping in the same way. #APCCC19 https://t.co/1h7XWt8uSl" / X
Piet Ost on X: "How does PARPinhibitors work? By Kim Chi. Not all molecules do PARP trapping in the same way. #APCCC19 https://t.co/1h7XWt8uSl" / X

Cancers | Free Full-Text | Clinical Landscape of PARP Inhibitors in Ovarian  Cancer: Molecular Mechanisms and Clues to Overcome Resistance
Cancers | Free Full-Text | Clinical Landscape of PARP Inhibitors in Ovarian Cancer: Molecular Mechanisms and Clues to Overcome Resistance

Rationale for combination therapies with poly(ADP-ribose) polymerase... |  Download Scientific Diagram
Rationale for combination therapies with poly(ADP-ribose) polymerase... | Download Scientific Diagram

The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP  Inhibitor Efficiency - ScienceDirect
The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency - ScienceDirect

Alternate therapeutic pathways for PARP inhibitors and potential mechanisms  of resistance | Experimental & Molecular Medicine
Alternate therapeutic pathways for PARP inhibitors and potential mechanisms of resistance | Experimental & Molecular Medicine

Trapping PARP-DNA complexes - anti-cancer drug screening - Tebubio's blog
Trapping PARP-DNA complexes - anti-cancer drug screening - Tebubio's blog

DNA repair and the effects of PARP inhibitor. When the DNA... | Download  Scientific Diagram
DNA repair and the effects of PARP inhibitor. When the DNA... | Download Scientific Diagram

PARPi that causes PARP1 trapping disrupts MYBBP1A chromatin... | Download  Scientific Diagram
PARPi that causes PARP1 trapping disrupts MYBBP1A chromatin... | Download Scientific Diagram

Classification of PARP Inhibitors Based on PARP Trapping and Catalytic  Inhibition, and Rationale for Combinations with Topoisomerase I Inhibitors  and Alkylating Agents | SpringerLink
Classification of PARP Inhibitors Based on PARP Trapping and Catalytic Inhibition, and Rationale for Combinations with Topoisomerase I Inhibitors and Alkylating Agents | SpringerLink

Studying PAR-Dependent Chromatin Remodeling to Tackle PARPi Resistance:  Trends in Molecular Medicine
Studying PAR-Dependent Chromatin Remodeling to Tackle PARPi Resistance: Trends in Molecular Medicine

Avoid the trap: Targeting PARP1 beyond human malignancy
Avoid the trap: Targeting PARP1 beyond human malignancy

Setting Better Traps for PARP Inhibitors | The Scientist Magazine®
Setting Better Traps for PARP Inhibitors | The Scientist Magazine®

PARP inhibitor BMN-673 induced apoptosis by trapping PARP-1 and inhibiting  base excision repair via modulation of pol-β in chromatin of breast cancer  cells - ScienceDirect
PARP inhibitor BMN-673 induced apoptosis by trapping PARP-1 and inhibiting base excision repair via modulation of pol-β in chromatin of breast cancer cells - ScienceDirect

Cancers | Free Full-Text | PARP Inhibitors in Melanoma—An Expanding  Therapeutic Option?
Cancers | Free Full-Text | PARP Inhibitors in Melanoma—An Expanding Therapeutic Option?

Clinical PARP inhibitors (PARPis) and determinants of response and... |  Download Scientific Diagram
Clinical PARP inhibitors (PARPis) and determinants of response and... | Download Scientific Diagram